The present invention relates to 1,3,5-trisubstituted
4,5-dihydro-1H-pyrazole derivatives as CB.sub.1 antagonists, to methods
for the preparation of these compounds and to novel intermediates useful
for the synthesis of said pyrazole derivatives. The invention also
relates to the use of a compound disclosed herein for the manufacture of
a medicament giving a beneficial effect.
The compounds have the general formula (I) 1
wherein the symbols have the meanings given in the specification.
