This invention is directed to a compound of the formula I 1
as defined herein, or a pharmaceutically acceptable salt thereof; a
pharmaceutical composition containing a compound of formula I, a method
of treatment of a disorder or condition that may be treated by modulating
histamine H3 receptors, the method comprising administering to a mammal
in need of such treatment a compound of formula I as described above, and
a method of treatment of a disorder or condition selected from the group
consisting of depression, mood disorders, schizophrenia, anxiety
disorders, Alzheimer's disease, attention-deficit hyperactivity disorder
(ADHD), psychotic disorders, sleep disorders, obesity, dizziness,
epilepsy, motion sickness, respiratory diseases, allergy, allergy-induced
airway responses, allergic rhinitis, nasal congestion, allergic
congestion, congestion, hypotension, cardiovascular disease, diseases of
the GI tract, hyper and hypo motility and acidic secretion of the
gastro-intestinal tract, the method comprising administering to a mammal
in need of such treatment a compound of formula I as described above.
