The present invention provides a compound of formula I: ##STR00001## or
a pharmaceutically acceptable salt or mixtures thereof. These compounds
are inhibitors of protein kinases, particularly inhibitors of GSK
mammalian protein kinase, and more particularly inhibitors of GSK-3
mammalian protein kinase. The invention also provides pharmaceutically
acceptable compositions comprising the compounds of the invention and
methods of utilizing those compounds and compositions in the treatment of
various protein kinase mediated disorders.