A system and method for data analysis are disclosed. Data analysis may include a step of filtering the data to produce filtered data. The method may include processing a plurality of prediction algorithms to produce prediction values, the prediction values having associated historical and expected prediction confidence intervals. The method may also include evaluating performance of the prediction algorithms to generate performance indexes, the performance indexes having associated index confidence intervals. The method may also include generating relevance values of the prediction algorithms based on the performance indexes, and index confidence intervals. The method may further include applying the relevance values and prediction confidence intervals to determine how to combine prediction values, and applying multivariable data fusion to combine the prediction values. The form of output of the data analysis may be chosen from a list of output options, including predictions, reports, warnings and alarms, and other forms of reporting.