A penetrating antibiotic gel for treating pain, inflammation and other pathological
conditions affecting musculoskeletal tissues and other soft tissues of the body.
The composition includes an antibiotic compound and a mobilizing agent in an amount
sufficient to enable the antimicrobial compound to penetrate into the sub-dermal
soft tissues. The antimicrobial compound may be a macrolide antibiotic compound
such as azithromycin, erythromycin or roxithromycin, for example, and the mobilizing
agent may be an organogel compound, such as pluronic lecithin liposomal organogel
(PLO). The composition may further include a penetration enhancing adjuvant, such
as d-limonene, for example. The composition may be applied topically so as to penetrate
into the sub-dermal soft tissues, or may injected so as to be absorbed into the
soft tissues locally.
