Antisense modulation of sphingosine-1-phosphate lyase expression

   
   

Antisense compounds, compositions and methods are provided for modulating the expression of sphingosine-1-phosphate lyase. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding sphingosine-1-phosphate lyase. Methods of using these compounds for modulation of sphingosine-1-phosphate lyase expression and for treatment of diseases associated with expression of sphingosine-1-phosphate lyase are provided.

Los compuestos, las composiciones y los métodos de Antisense se proporcionan para modular la expresión del lyase de sphingosine-1-phosphate. Las composiciones abarcan los compuestos del antisense, particularmente oligonucleotides del antisense, apuntados a los ácidos nucleic que codifican el lyase de sphingosine-1-phosphate. Los métodos de usar estos compuestos para la modulación de la expresión del lyase de sphingosine-1-phosphate y para el tratamiento de las enfermedades asociadas a la expresión del lyase de sphingosine-1-phosphate se proporcionan.

 
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