Apparatus for treatment is provided, including one or more electrodes,
configured to be applied to a site of a subject, and adverse
cerebrovascular condition treatment functionality. The functionality
comprises a control unit configured to drive the one or more electrodes
to apply electrical stimulation to the site during a plurality of
stimulation periods which includes at least first and last stimulation
periods, set an inter-period interval between initiation of the first
stimulation period and initiation of the last stimulation period to be at
least 24 hours, and configure the stimulation during the first and last
stimulation periods to induce at least one neuroprotective occurrence
selected from the group consisting of: an increase in cerebral blood flow
(CBF) of the subject, and a release of one or more neuroprotective
substances. The site is selected from the group consisting of: a
sphenopalatine ganglion (SPG), a greater palatine nerve, a lesser
palatine nerve, a sphenopalatine nerve, a communicating branch between a
maxillary nerve and an SPG, an otic ganglion, an afferent fiber going
into the otic ganglion, an efferent fiber going out of the otic ganglion,
an infraorbital nerve, a vidian nerve, a greater superficial petrosal
nerve, and a lesser deep petrosal nerve. Additional embodiments are also
described.