The present invention provides a method and system for powderizing a liquid form treated material into powder form including a treatment housing with a powderization chamber, a collection base, an injection nozzle on the top of the treatment housing, a drying unit in a lower portion of the treatment housing, and an moisture air passage provided in an upper portion of the treatment housing and a filter unit. The drying unit having a drying air passage to facilitate a tangentially injection of the air flowing therethrough into the powderization chamber. When the liquid form treated materials is injected into the powderization chamber, and a dry airflow is provided, an airflow is created. As a result, the reaction rate is greatly increased, the chance and time of decomposition of enzyme or protein during powderization is much lowered such that the resulting powder maintain a content of high enzyme activity and high nutrition value.