The invention is concerned with novel heterocyclyl substituted 1-alkoxy acetic acid derivatives of formula (I) ##STR00001## wherein R.sup.1 to R.sup.6 and A are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit the formation of coagulation factors Xa, IXa and thrombin induced by factor VIIa and tissue factor and can be used as medicaments.