Pharmaceutical preparation containing an effective amount of acetylsalicylic acid and a compound of Formula I.

A1—A2—NH—(CH2)n—B

    • wherein A1, A2, n and B are as defined in the specification, which is either the compound as such, or a stereoisomer thereof, and which may be in the form of a physiologically acceptable salt, in association with a pharmaceutical carrier. The combinations are suitable for use in inhibiting thrombin, or in the treatment or prophylaxis of thrombosis or hypercoagulability in patients in need thereof.
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