The present invention relates to variants of serine proteases having decreased
immunogenicity relative to their corresponding wild-type proteases. More particularly,
the present invention relates to variants having a modified amino acid sequence
of a wild-type amino acid sequence, wherein the modified amino acid sequence comprises
a deletion and, optionally, a substitution of one or more specifically identified
positions corresponding to subtilisin BPN. The invention further relates
to mutant genes encoding such variants and cleaning and personal care compositions
comprising such variants.
