Drosophila melanogaster p70S6 kinase

   
   

The invention provides Drosophila melanogaster p70.sup.S6K, as well as nucleic acids encoding this kinase. The sequence of Drosophila p70.sup.S6K and the gene encoding it are represented in SEQ ID No. 2 and 1 respectively. The invention moreover provides mutated forms of Drosophila p70.sup.S6K, including constitutively active and dominant negative forms thereof, which are useful in the study of p70.sup.S6K activity. Furthermore, the invention provides expression systems which produce Drosophila p70.sup.S6K in Drosophila and other organisms, and in particular systems in which expression of Drosophila p70.sup.S6K has been modulated so as to facilitate the study of its activity.

A invenção fornece o melanogaster p70.sup.S6K da drosófila, as.well.as os ácidos nucleic que codificam este kinase. A seqüência da drosófila p70.sup.S6K e o gene que codifica a são representados em ID SEQ no. 2 e 1 respectivamente. A invenção além disso fornece formulários mutated da drosófila p70.sup.S6K, including os formulários negativos constitutively ativos e dominantes disso, que são úteis no estudo da atividade de p70.sup.S6K. Além disso, a invenção fornece os sistemas da expressão que produzem a drosófila p70.sup.S6K na drosófila e nos outros organismos, e nos sistemas particulares em que a expressão da drosófila p70.sup.S6K foi modulada para facilitar o estudo de sua atividade.

 
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