Substituted N,N-disubstituted diamino compounds useful for inhibiting cholesteryl ester transfer protein activity

The invention relates to substituted polycyclic aryl and heteroary tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating atherosclerosis and other coronary artery diseases. Preferred tertiary-heteroalkylamine compounds are substituted N,N-disubstituted diamines. A preferred specific N,N-disubstituted diamine is the compound: ##STR1##
Вымысел относит к замененному полициклическому арилу и heteroary treticnym-heteroalkylamine смесям полезным по мере того как иы АБС битор эстера холестерила переносят протеин (CETP; protein-4 переноса липида плазмы) и смеси, составы и методы для обрабатывать атеросклероз и другие заболевания коронарной артерии. Предпочитаемые treticnye-heteroalkylamine смеси будут замененным н, Н-n-disubstituted диаминами. Предпочитаемым специфически н, Н-n-disubstituted диамин будет смесь: ## ## STR1

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