The invention relates to compounds of formula I and to their physiologically acceptable salts and solvates which act as phosphodiesterse VII inhibitors and are thus useful for the treatment of allergic disorders, asthma, chronic bronchitis, atopic dermatitis, psoriasis and other skin disorders, inflammatory disorders, autoimmune diseases, rheumatoid arthritis, multiple sclerosis, Crohn's disease, diabetes mellitus or ulcerative colitis, osteoporosis, transplant rejection reactions, cachexia, tumor growth, tumor metastases, sepsis, memory disturbances, atherosclerosis and AIDS.

A invenção relaciona-se aos compostos da fórmula I e a seus sais e solvates physiologically aceitáveis que agem como inibidores do phosphodiesterse VII e são assim úteis para o tratamento de disorders allergic, asthma, bronchitis crônico, dermatite atópica, psoriasis e outros disorders da pele, disorders inflammatory, doenças autoimmune, arthritis rheumatoid, sclerosis múltiplo, doença de Crohn, mellitus do diabetes ou colitis, osteoporosis, reações da rejeção do transplant, caquexia, crescimento do tumor, metastases do tumor, sepsis, distúrbios da memória, atherosclerosis e AIDS ulcerative.