A cosmetic process for caring for human skin, intended for preventing or combating the cutaneous signs resulting from non-pathological impairment of the barrier function, includes the topical application to the skin of a composition containing at least one active agent for stimulating the expression of FN3K and/or FN3K RP. The use of this active agent for preventing or combating the cutaneous signs resulting from non-pathological impairment of the barrier function is also disclosed.