In the method of playing a professional boxing fantasy league game players select names of real professional boxers from a database to staff their fantasy gyms and manage the fantasy gyms during a season in which real boxing matches take place between the selected boxers to determine which of the players is better at selecting and managing the boxers for his or her fantasy gym. The fantasy boxing competition is scored by assigning boxer point values according to a predetermined, unique and specific set of criteria according to the actual results of real boxing matches that take place between the selected boxers during the game. A cumulative total of gym points for each gym based on the boxer point values acquired by the boxers of the gym when they are active and on the gym roster determines the competition winner.