Disclosed are compounds which bind VLA-4. Certain of these compounds also inhibit leukocyte adhesion and, in particular, leukocyte adhesion mediated by VLA-4. Such compounds are useful in the treatment of inflammatory diseases in a mammalian patient, e.g., human, such as asthma, Alzheimer's disease, atherosclerosis, AIDS dementia, diabetes, inflammatory bowel disease, rheumatoid arthritis, tissue transplantation, tumor metastasis and myocardial ischemia. The compounds can also be administered for the treatment of inflammatory brain diseases such as multiple sclerosis.

 
Web www.patentalert.com

< Nonaqueous secondary battery

< Nonaqueous electrolyte secondary battery

> Propylene copolymer, polypropylene composition and uses thereof, transition metal compound and olefin polymerization catalyst

> Process for preparing lithium manganate

~ 00612