The invention concerns the use of stabilized oligonucleotides comprising at least an octamer motif of the type: 5'-purine-purine-CG-pyrimdine-pyrimidine-X.sub.1X.sub.2-3' wherein the pair X.sub.1-X.sub.2 is AT, AA, CT or TT, for preparing a medicine with antitumour activity.

 
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> Process for constructing strain having compactin hydroxylation ability

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