Compositions may include long-chain organic molecules obtained from natural oils, particularly plant, bean, seed and nut oils, and their derivatives can be provided with increased oxygen stability by their combination with mixtures of particular classes of antioxidants, particularly combinations of at least one synthetic free-radical terminating antioxidant. The stabilization combination is particularly effective in combination with long-chain oils having less than 5% methylene interrupted unsaturation and free-radical terminating antioxidants present in an amount of from 0.001 to 5% or more by weight of the long-chain oils. The long-chain oil may include a natural oil or wax, such as Macadamia oil and its derivatives, Moringa oil and its derivatives, Babassu oil and its derivatives, Meadowfoam oil and its derivatives, and High Oleic Sunflower oil.