The present invention is directed to certain hydroisoindoline compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including emesis, urinary incontinence, depression, and anxiety.

 
Web www.patentalert.com

< Triazole compounds and uses related thereto

> 3-substituted-4-pyrimidone derivatives

> 4-aminopiperidine derivatives

~ 00590