The present invention provides a therapeutic agent for hyperlipidemia having an excellent effect of lowering the cholesterol and triglyceride level in blood plasma. The present invention relates to a prophylactic and/or therapeutic agent for hyperlipidemia, a prophylactic and/or therapeutic agent for obesity or diabetes mellitus, and a prophylactic and/or therapeutic agent for metabolic syndrome, each agent including a compound represented by the following formula (1): ##STR00001## , wherein:R.sup.1 and R.sup.2, which may be identical or different, each represent a hydrogen atom, a methyl group or an ethyl group; R.sup.3a, R.sup.3b, R.sup.4a and R.sup.4b, which may be identical or different, each represent a hydrogen atom, a halogen atom, a nitro group, a hydroxyl group, a C.sub.1-4 alkyl group, a trifluoromethyl group, a C.sub.1-4 alkoxy group, a C.sub.1-4 alkylcarbonyloxy group, a di-C.sub.1-4 alkylamino group, a C.sub.1-4 alkylsulfonyloxy group, a C.sub.1-4 alkylsulfonyl group, a C.sub.1-4 alkylsulfinyl group, or a C.sub.1-4 alkylthio group, or R.sup.3a and R.sup.3b, or R.sup.4a and R.sup.4b are joined to represent an alkylenedioxy group; X represents an oxygen atom, a sulfur atom or N--R.sup.5 (wherein R.sup.5 represents a hydrogen atom, a C.sub.1-4 alkyl group, a C.sub.1-4 alkylsulfonyl group, or a C.sub.1-4 alkyloxycarbonyl group); Y represents an oxygen atom, a S(O)l group (l represents a number from 0 to 2), a carbonyl group, a carbonylamino group, an aminocarbonyl group, a sulfonylamino group, an aminosulfonyl group, or an NH group; Z represents CH or N; n represents a number from 1 to 6; and m represents a number from 2 to 6, or a salt thereof, and a statin, particularly pitavastatin, in combination.