A medical device system includes a brain monitoring element,
cardiopulmonary monitoring element, therapy module and a processor. The
processor is configured to activate the therapy module upon detection of
a cardiopulmonary event in the cardiopulmonary signal. The processor is
further configured to monitor the brain signal and communicate to the
therapy module to change the cardiopulmonary triggered therapeutic output
to the brain based upon the brain monitoring. Methods of treating a
person with a neurological disorder are also provided.