Software hints embedded in branch instructions direct selection of one of a plurality of branch predictors to use when processing the branch instructions, leading to improved branch prediction (i.e. fewer mis-predictions) over conventional schemes. A software agent assembles branch instructions having associated respective branch predictor control fields compatible with a branch predictor selector and a plurality of branch predictors. Each branch predictor control field is used to perform branch predictor selection, branch predictor control, or both. Branch predictor selection enables selective branch prediction according to an appropriate one of the branch predictors as determined by the software agent by examining context surrounding the branch instruction. Branch predictor control enables control of operation of one or more of the branch predictors. For example, a history-based branch predictor may be instructed to provide branch prediction according to a history-depth specified by the branch predictor control.