Methods are disclosed for caching content and state data at a network element. In one embodiment, data packets are intercepted at a network element. An application layer message, which specifies a request for specified data from a server application, is determined from the data packets. A first portion of the specified data contained in the network element's cache is determined. A message that requests a second portion of the data not contained in the cache is sent toward a server application. A first response that contains the second portion, but not the first portion, is received. A second response, which contains the first and second portions, is sent toward a client application.In one embodiment, data packets are intercepted at the network element. An application layer message, which specifies session or database connection state information, is determined from the data packets. The state information is cached at the network element.