A barrier membrane for guided bone regeneration and a method of manufacturing the same are provided. The barrier membrane for guided bone regeneration that is made of silver, gold, or gold alloy includes a substrate having texture including protrusions with a predetermined shape, a polymer layer formed by coating an upper surface of the substrate with polymer solution, and a bio-ceramic layer formed by coating a lower surface of the substrate. It is possible for the barrier membrane for guided bone regeneration to secure biocompatibility, exclusion and sealing of cells, space maintenance, connectivity with tissues, and easiness of using the barrier membrane which are required for guided bone/tissue regeneration (GBR/GTR).