The invention provides a dual compartment pouch having first and second compartments that are separated from each other by an impervious inner sheet having a breathable membrane. The breathable membrane comprises a breathable material that is pervious to moisture and gases, and impervious to liquids as well as microorganisms. The breathable membrane allows a sterilizing gas to be introduced between the first and second compartments. The front and back sheets are sealed to the inner sheet to define the first and second compartments in which the inner sheet forms a common wall between the compartments. The breathable membrane is disposed towards a central portion of the inner sheet and is spaced apart from the seams joining the front and back sheets to the inner sheet. In one embodiment, a sterilized article is disposed in one compartment, and an absorbent packets are disposed in the other compartment.