A workflow for a minimally invasive intervention, such as a treatment for a cancerous tumor, includes positioning a patient at a multi-functional imaging apparatus, obtaining pre-interventional images of the anatomy of the patient using a computed tomography or angiography imaging function, performing the minimally invasive intervention while the patient is positioned at the multi-functional imaging apparatus and while using a fluoroscopic imaging function, and performing a post-interventional imaging of the patient's anatomy while the patient is positioned at the multi-functional imaging apparatus using the computed tomography or angiographic imaging function. If the post-interventional imaging determines that additional intervention is in order, the additional intervention is performed while the patient is positioned at the imaging apparatus. Pre-intervention images and data sets from other sources may be combined with or used during the intervention. A treatment planning step may be included following the pre-interventional imaging and the intervention.