A receiver includes an input circuit, which is coupled to at least one antenna so as to receive, process and digitize first and second signals, thus generating first and second streams of input samples. An interference cancellation circuit in the receiver includes first and second adaptive filters, which are respectively coupled to filter the first and second streams of input samples using respective first and second coefficients to generate respective first and second filter outputs. A phase rotator is adapted to apply a variable phase shift compensating for a phase deviation between the first and second signals, the phase rotator having at least one configuration parameter. A control module is operative to estimate signal characteristics of the interference cancellation circuit and to set the at least one configuration parameter of the phase rotator responsively to the estimated signal characteristics.