A nucleotide analogue compound represented by formula (1) and salts thereof. In formula (1), A represents a direct bond, C.sub.1-4 alkylene, etc.; B represents an optionally substituted aromatic heterocyclic groups; and R.sub.1, R.sub.2, R.sub.3 and R.sub.4 each represents hydrogen, an amino-protecting group, a hydroxyl-protecting group, a phosphate group, or --P(R.sub.7)R.sub.8, wherein R.sub.7 and R.sub.8 each represents hydroxyl, protected hydroxyl, mercapto, protected mercapto, etc. The compounds are useful as nucleotide analogues for producing oligonucleotide analogues useful in an antisense method and for producing intermediates thereof.