The invention provides vitamin K-dependent polypeptides with enhanced membrane binding affinity. These polypeptides can be used to modulate clot formation in mammals. Methods of modulating clot formation in mammals are also described.

 
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> Method for preparing clopidogrel 1,5-naphthalenedisulfonate or hydrate thereof

> .DELTA. 5 desaturase and its use in making polyunsaturated fatty acids
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