Provided are compositions and methods for treating or preventing lung or
respiratory disorders or conditions characterized by airflow obstruction
or limitation, or a symptom thereof (e.g., asthma, rhinitis, allergic
rhinitis (e.g. nose respiratory tract), and chronic obstructive pulmonary
disease (COPD) and COPD-associated conditions (e.g., bronchitis,
emphysema, asthma), emphysema, pneumonia, bronchitis, influenza, SARS,
tuberculosis, and whooping cough (pertussis), and the like) in a subject
in need thereof by administering a therapeutic composition comprising at
least one electrokinetically generated fluid (including gas-enriched
electrokinetically generated fluids) as disclosed herein, the
electrokinetically altered aqueous fluid suitable to alter cellular
membrane structure or function sufficient to provide for modulation of
intracellular signal transduction, wherein treating a lung disorder or a
symptom thereof is thereby afforded. Additional aspects relate to
therapeutic compositions, and combination treatment methods comprising
administration of at least one electrokinetically generated fluid in
combination with at least one additional therapeutic agent.