A preamble retransmission method in an Evolved Mobile Telecommunications System (E-UMTS) system is provided by which a terminal transmits a Radio Access Channel (RACH) preamble to a base station, the base station compares the received RACH preamble with preset specific criteria and requests retransmission for the RACH preamble to the terminal according to the comparison in order to reduce the probability of data transmission failure due to inaccuracy of time synchronization and to decrease interference with transmissions by other terminals.