A system and method for efficiently detecting and correcting transmission errors in packet-based communications by using cumulative error detection codes. The system may comprise a transmitting unit, which transmits one or more data packets. Each of the transmitted packets may comprise a plurality of transmission subunits. The transmitting unit preferably generates a cumulative error detection code (e.g., cumulative CRC code) for each of the transmission subunits of a packet. The system may further comprise a receiving unit to receive each of the transmission subunits of the packet. The receiving unit preferably generates a new cumulative error detection code for each of the received transmission subunits. The new cumulative error detection code is compared to the received cumulative error detection code to determine if any errors occurred in the transmission of the transmission subunit.