This application concerns certain 4-cyanophenylamino-substituted bicyclic heterocycles of formula I ##STR00001## where the dashed line represents a double bond that may be located either between A and C(V) or between C(V) and D, where A is S or C(Z); D is S or C(W); provided that one and only one of A and D is S; where T is NH, O, or S; and where other substituents are defined herein. These compounds are non-nucleoside reverse transcriptase inhibitors and have potential as anti-HIV treatment.

 
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> Broadspectrum 2-(substituted-amino)-benzoxazole sulfonamide HIV protease inhibitors

> IGG1 monoclonal antibody with anti-HIV neutralizing activity

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