A peristaltic roller pump includes a rotor carrying a pumping roller on one end and an occluding roller on the other end. Occluding roller has a number of protrusions designed to only occlude the tubing section that is located under that roller as it moves over it in order to prevent any back flow through that section of the tube. Occluding roller is designed to not cause any pumping of fluid through the section of the tubing under that roller. Such design is useful in a single-needle dialysis system and in other alternating pumping systems in which during a first phase of the pumping the fluid is moved in one direction and during the second phase of operation the fluid is moved in the opposite direction.

 
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