A vapor-permeable and waterproof sole for shoes, including at least one first load-bearing component, including at least one vapor-permeable or perforated portion, including a vapor-permeable or perforated filler, at least one second component, predominantly arranged below the first component with a tread provided thereon. The second component includes through perforations at the vapor-permeable or perforated portion of the first component. Below the vapor-permeable or perforated portion and above the tread a membrane water impermeable and of water vapor permeable material is provided. The first component is constituted by a plastic midsole. The midsole is rigidly coupled to the membrane and to the filler by molding before providing the tread. A single peripheral seal is provided on the membrane formed by the molding of the midsole; the midsole surrounds peripherally the membrane.