Heterogeneous processors can cooperate for distributed processing tasks in a multiprocessor computing system. Each processor is operable in a "compatible" mode, in which all processors within a family accept the same baseline command set and produce identical results upon executing any command in the baseline command set. The processors also have a "native" mode of operation in which the command set and/or results may differ in at least some respects from the baseline command set and results. Heterogeneous processors with a compatible mode defined by reference to the same baseline can be used cooperatively for distributed processing by configuring each processor to operate in the compatible mode.