A system, method, and computer program product for automatically adjusting the output of presentation content based upon vehicle conditions. The method determines whether one of a plurality of vehicle conditions exists, such as conditions related to vehicle speed, rate of change in vehicle speed, rate of change in vehicle direction, vehicle emergencies, cellular phone or headphone activation, radar detector activation, noise level decibels above a certain value, etc. The method determines an output format based on the determined vehicle conditions. The method outputs at least a portion of the presentation content based on the determined output format. The determined output format includes display format information, such as text font or icon size information or map detail. The presentation content can also include audio content.