The present disclosure provides for improved methods for treating pain, including pain associated with chronic inflammatory diseases, neuropathic pain and cancer by using .alpha.-adrenergic antagonists and .beta.-adrenergic agonists (particularly .beta..sub.2-adrenergic agonists) alone or in combination.

 
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< Spatially-defined macrocycles incorporating peptide bond surrogates

> Process for manufacture of pure (2S, 3aS, 7aS)-1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl) butyl]amino]-1-oxopropyl] octahydro-1H-indole-2-carboxylic acid and its tert. butyl amine salt

> Mechanism-based targeted pancreatic beta cell imaging and therapy
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