A virtual 4D treatment suite includes a dose calculation module, a gating module, and a dose rate adjustment module. The 4D treatment suite may be used to virtually analyze the impact the motion of a target tissue has on therapy for a particular patient and a proposed treatment plan. For example, for a proposed treatment plan, the dose calculation module may calculate a dose that would be received by a target tissue and an associated dose temporal variation based on an identified movement of the target tissue relative to at least a portion of a treatment field. Based on the calculated expected therapy dose and dose temporal variation, the gating module may determine whether to implement a gating technique for the proposed treatment plan and/or the dose rate adjustment module may determine whether to adjust the dose rate of the proposed treatment plan.