Apparatus and methods provide an operational transconductance amplifier (OTA) with one or more self-biased cascode current mirrors. Applicable topologies include a current-mirror OTA and a folded-cascode OTA. In one embodiment, the self-biasing cascode current mirror is an optional aspect of the folded-cascode OTA. The self-biasing can advantageous reduce the number of biasing circuits used, which can save chip area and cost. One embodiment includes an input differential pair of a current-mirror OTA.