The invention relates to bone health compositions comprising an acidic
protein fraction of milk, to a method of producing said bone health
composition, to methods of treatment comprising said bone health
compositions and to medicinal uses of said bone health compositions. One
broad aspect of the invention provides a bone health composition
comprising an acidic protein fraction derived from milk, from a component
of milk, from whey, from hydrolysates thereof, or from a combination
thereof wherein the composition does not comprise
caseinoglycomacropeptide (CGMP). Another broad aspect provides a method
of manufacturing the composition of the invention using anion exchange
chromatography.