A system and method for identifying, locating, and managing inventory of sterilized medical devices located within a sealed sterilization case in preparation for a surgical procedure. Communication tags, such as radio frequency identification (RFID) and/or Global Positioning System (GPS) tags, are connected to the medical device and communicate information wirelessly. Information is obtained from the communication tags and sent to the database where it is compared with the information in the database. The results may be displayed on the interface thereby providing the user with information about the medical instruments contained in the sealed sterilization case without breaking the seal of the sealed sterilization case.