The present invention relates to racemized proteins and racemized protein
components of spherons that are useful for identifying compounds capable
of preventing and/or ameliorating symptoms of Alzheimer's Disease and/or
dementia associated with cerebral amyloidosis. The invention also relates
to the compounds identified by the methods, and methods of treating
and/or ameliorating symptoms of Alzheimer's Disease and/or dementia
associated with cerebral amyloidosis. The invention also relates to
methods of making an Alzheimer's Disease or dementia associated with
cerebral amyloidosis animal model or test animal, the animal model
produced therefrom, and to a method of using the animal model to screen
for effective therapies.