Compounds of the formula (I): ##STR00001## as well as pharmaceutically acceptable salts and esters thereof, wherein R.sup.1 to R.sup.5 have the significance given in claim 1 can be used in the form of pharmaceutical compositions.

 
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> Indol-2-yl-piperazin-1-yl-methanone derivatives

> Substituted 8'-pyridinyl-dihydrospiro-[cycloalkyl]-pyrimido[1,2-a] pyrimidin-6-one and 8'-pyrimidinyl-dihydrospiro-[cycloalkyl]-pyrimido[1,2-a] pyrimidin-6-one derivatives
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