A system and method for cleanup of biological samples from contaminants
prior to spectroscopy analysis. The system includes a support configured
to hold a sample including a liquid having at least one group of
biological molecules with a surface of the support binding the molecules
at a surface tension angle to the liquid of less than 180 degrees. The
system includes an evaporator configured to evaporate liquid from the
support, a solvent applicator configured to apply a solvent for
dissolution of the contaminants in the sample, and a solvent removal
device configured to remove applied solvent from the sample and thereby
at least partially remove the contaminants.