Color measurements are generated from transform-based device profiles for use in a measurement-based color management system. The color measurements is generated by providing device-dependent color samples to a transform-based color management module and converting them to the profile connection space with the device's transform-based profile. Color measurements are then generated from the transform-based color management module by applying an identity profile in place of a destination device profile. In addition, measurement data can be extracted directly from either the tone reproduction curve/matrix or n-dimensional lookup table transforms contained within a transform-based device profile.