The present invention relates to flea GABA receptor subunit nucleic acid
molecules; to flea GABA receptor subunit proteins encoded by such nucleic
acid molecules; to antibodies raised against such proteins; and to
compounds that inhibit the activity of such proteins. The present
invention also includes methods to obtain such proteins, nucleic acid
molecules, antibodies, and inhibitory compounds. The present invention
also includes therapeutic compositions comprising such proteins, nucleic
acid molecules, antibodies and inhibitory compounds, particularly those
that specifically inhibit flea GABA receptor subunit activity, as well as
the use of such therapeutic compositions to treat animals.