An antitumor effect enhancer for enhancing the antitumor effects of an antitumor substance, which comprises a compound represented by the following formula (1): ##STR00001## wherein each R independently represents a hydrogen atom, a lower alkyl group, an aryl group, an allyl group, an aralkyl group, a halogen atom, a hydroxyl group, an amino group, R'O--, R'(C.dbd.O)--, R'(C.dbd.O)O--, or R'O(C.dbd.O)--, wherein R' is an alkyl group containing 1 to 5 carbon atoms, or a pharmaceutically acceptable salt thereof.

 
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