A method and system for enabling multiple users from different physical locations to access, observe, control and manipulate physical processes and devices over a computer network such as the Internet is disclosed. A user may visually monitor the physical set up and state of an experiment or environment by receiving live video and data, as well as directly control instrumentation while receiving live feedback regarding the input commands. Measurement data may be collected into a database and computational analysis can be generated and displayed as a physical process is being performed. An online interactive laboratory notebook is also provided that manages items such as collected data, laboratory parameters, "to do" lists, personal notes, etc.